Fold Designability, Distribution and Disease
نویسندگان
چکیده
منابع مشابه
Fold Designability, Distribution, and Disease
Fold designability has been estimated by the number of families contained in that fold. Here, we show that among orthologous proteins, sequence divergence is higher for folds with greater numbers of families. Folds with greater numbers of families also tend to have families that appear more often in the proteome and greater promiscuity (the number of unique "partner" folds that the fold is foun...
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ژورنال
عنوان ژورنال: PLoS Computational Biology
سال: 2005
ISSN: 1553-734X,1553-7358
DOI: 10.1371/journal.pcbi.0020040.eor